Injection: Adverse reactions are mainly gastrointestinal disorders and hypersensitivity pneumonitis. The appearance of the latter is mostly in individuals who have previously shown hypersensitivity reactions to pharmaceutical products and other substances and in those who have a previous case history of allergy, asthma, hay fever and urticaria.
In general, patients treated with cephalosporins have had the following undesirable reactions reported during or after treatment: Glossitis, nausea, vomiting, gastric pyrosis, abdominal pain and diarrhea. Very rare: Cutaneous rash, pruritus, urticaria and arthralgia were also reported.
Occasionally, transient and recoverable changes in some laboratory parameters eg, eosinophilia, leukopenia, and increased serum transaminase, total bilirubin and blood urea nitrogen (BUN) were reported. Other reactions observed were vertigo with sensation of thoracic constriction and candida vaginitis, with appearance of the latter related to the development of nonsusceptible organisms. These adverse reactions should be treated properly and closely monitored by physicians to determine whether a discontinuation of therapy is necessary.
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