Cleargut

Cleargut

lactulose

Manufacturer:

Magbro Healthcare

Distributor:

Alkem Lab
Concise Prescribing Info
Contents
Lactulose
Indications/Uses
Constipation (regulation of physiological rhythm of the colon); where soft stool is considered of medical benefit (in hemorrhoids, post colonic/anal surgery). Treatment & prevention of hepatic coma or precoma (hepatic encephalopathy).
Dosage/Direction for Use
Constipation or where soft stool is considered of medical benefit May be given as single daily dose or in 2 divided doses. Adjust starting dose to maintenance dose after few days based upon treatment response. May need several days (2-3 days) before treatment effect occurs. Adult & adolescent Starting dose: 15-45 mL daily. Maintenance dose: 15-30 mL daily. Childn 7-14 yr Starting dose: 15 mL daily. Maintenance dose: 10-15 mL daily, 1-6 yr Starting & maintenance dose: 5-10 mL daily. Infant <1 yr Starting & maintenance dose: Up to 5 mL daily. Drink sufficient amounts of fluids (1.5-2 L, equal to 6-8 glasses) during the day. Hepatic encephalopathy Adult Starting dose: 20-30 g or 30-45 mL tid to qid. Dose may be adjusted to maintenance dose to achieve 2-3 soft stools/day.
Administration
May be taken with or without food: Swallow dose immediately, do not keep in mouth for an extended period of time. For single daily dose, take at the same time eg, during breakfast.
Special Precautions
Painful abdominal symptoms of undetermined cause before treatment is started; insufficient therapeutic effect after several days. Patients who are intolerant to lactose. Dose used in treatment of hepatic encephalopathy may need to be taken into consideration for diabetics. Chronic use of unadjusted doses & misuse can lead to diarrhea & disturbance of electrolyte balance. Contains lactose, galactose & small amounts of fructose. Not to be taken by patients w/ rare hereditary problem of galactose or fructose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Childn (newborn to 18 yr) w/ hepatic encephalopathy. Defecation reflex could be disturbed during treatment in childn.
Adverse Reactions
Diarrhea. Flatulence, abdominal pain, nausea, vomiting.
MIMS Class
Laxatives, Purgatives
ATC Classification
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Presentation/Packing
Form
Cleargut oral soln 3.33 g/5 mL
Packing/Price
(with 10-mL plastic measuring cap) 120 mL x 1's
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