Corplet Special Precautions

General: Clopidogrel prolongs the bleeding time and therefore should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery, or other pathological conditions.
GI Bleeding: Clopidogrel should be used with caution in patients who have lesions with a susceptibility to bleed such as ulcers.
Drugs that might induce such lesions should be used with caution in patients taking clopidogrel.
Hepatically Impaired Patients: Clopidogrel should be used with caution in hepatically impaired patients, as there is no study to indicate the safety of clopidogrel in patients with severe hepatic disease who may have bleeding diatheses.
Renally Impaired Patients: Clopidogrel should used with caution in patients with severe renal impairment, as there is no information about its safety in these patients.
Use in Pregnancy: See Use in Pregnancy & Lactation section for further information.
Use in Lactation: See Use in Pregnancy & Lactation section for further information.
Use in Children: Use Safety and effectiveness in the pediatric population have not been established.