Hypersensitivity to active substance levofloxacin or to other quinolones, to dexamethasone, or to other steroids, or to any of the excipients;
Herpes simplex keratitis, varicella and other viral disease of the cornea and conjunctiva;
Mycobacterial infections of the eye caused by, but not limited to, acid-fast bacilli such as Mycobacterium tuberculosis, Mycobacterium leprae, or Mycobacterium avium;
Fungal diseases of ocular structures;
Untreated purulent infection of the eye.