Dutarid Use In Pregnancy & Lactation

Dutasteride is contraindicated for use by women.
Pregnancy: As with other 5 alpha-reductase inhibitors, Dutasteride inhibits the conversion of testosterone to dihydrotestosterone and may, if administered to a woman carrying a male fetus, inhibit the development of the external genitalia of the fetus. Small amounts of Dutasteride have been recovered from the semen in subjects receiving Dutasteride 0.5 mg day. It is not known whether a male fetus may be adversely affected if his mother is exposed to the semen of a patient being treated with Dutasteride (the risk of which is greatest during the first 16 weeks of pregnancy).
As with all 5 alpha-reductase inhibitors, when the patient's partner is or may potentially be pregnant it is recommended that the patient avoids exposure of his partner to semen by use of a condom.
Breastfeeding: It is not known whether Dutasteride is excreted in human milk.
Fertility: Dutasteride has been reported to affect semen characteristics (reduction in sperm count, semen volume, and sperm motility) in healthy men. The possibility of reduced male fertility cannot be excluded.