Escitalopram should not be used in the treatment of children and adolescents under the age of 18 years.
Some patients with panic disorder may experience increased anxiety symptoms at the beginning of the treatment with antidepressants.
Escitalopram should be discontinued if the patients develops seizures for the first time, or if there is an increased in seizures frequency (in patients with a previous diagnosis of epilepsy).
It should be used with caution in patients with a history of mania/hypomania, diabetes.
Caution is advised in patients taking SSRIs, particularly in concomitant use with oral anticoagulants, with medicinal products known to affect platelet function and in patients with known bleeding.
Caution is advised if escitalopram is used concomitantly with medicinal products with serotonergic effects such as sumatriptan or other triptans, tramadol and tryptophan.
Caution is advised if escitalopram is used concomitantly with herbal remedies containing St. John's wort, it may result in an increased incidence of adverse reactions.