Ezoprole Adverse Reactions

The most frequently reported adverse effects with esomeprazole include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth.
Infections and Infestations: Fungal infection, herpes simplex, moniliasis, viral infection.
Neoplasms benign, malignant, and unspecified (including cysts and polyps): Benign gastrointestinal neoplasm, carcinoid tumor of the stomach, fundic gland polyps (benign), neoplasm progression.
Blood and lymphatic system disorders: Agranulocytosis, anemia, bilirubinemia, cervical lymphadenopathy, hypochromic anemia, leukocytosis, leukopenia, pancytopenia, thrombocytopenia.
Immune system disorders: Anaphylactic reaction/shock, angioedema, systemic lupus erythematosus.
Endocrine disorders: Goiter, hyperparathyroidism, hypothyroidism.
Metabolism and nutrition disorders: Anorexia, dehydration, facial edema, generalized edema, hypercholesterolemia, hyperuricemia, hypocalcemia, hypokalemia, hypomagnesemia, hyponatremia, increased appetite, leg edema, peripheral edema, thirst, vitamin B₁₂ deficiency.
Psychiatric disorders: Aggression, agitation, anxiety, apathy, confusion, depression, hallucinations, insomnia, nervousness, sleep disorder, somnolence.
Nervous system disorders: Carpal tunnel syndrome, dizziness, hyperesthesia, hypoesthesia, migraine, paresthesia, tremor.
Eye disorders: Blurred vision, conjunctivitis, visual field defect.
Ear and labyrinth disorders: Earache, ear infection, otitis media, tinnitus, vertigo.
Cardiac disorders: Chest pain, substernal chest pain, tachycardia.
Vascular disorders: Epistaxis, hot flushes, hypertension.
Respiratory, thoracic, and mediastinal disorders: Asthma, bronchitis, bronchospasm, cough, dyspnea, parosmia, pharyngitis, pharyngolaryngeal pain, respiratory tract infection, rhinitis, rhinorrhea, sinusitis, tachypnea.
Gastrointestinal disorders: Abdominal rigidity, Barrett's esophagus, Clostridium difficile-associated diarrhea, defecation urge, duodenitis, dyspepsia, dysphagia, enlarged abdomen, epigastric pain, erosive gastritis, eructation, esophageal disorder, gastric retention, gastric ulcer, gastritis, gastroenteritis, gastrointestinal candidiasis, gastrointestinal dysplasia, gastrointestinal hemorrhage, gastrointestinal tract mucosal discoloration, gingival abscess, hiccup, melena, microscopic colitis, pancreatitis, regurgitation, stomatitis, taste disturbance, taste loss, tooth disorder, ulcerative stomatitis, vomiting.
Hepatobiliary disorders: Hepatic encephalopathy, hepatic failure, hepatitis with or without jaundice, increased liver enzymes.
Skin and subcutaneous tissue disorders: Acne, alopecia, dermatitis, erythema multiforme, erythematous rash, maculopapular rash, photosensitivity, pruritus, rash, skin inflammation, Stevens-Johnson syndrome (SJS), subacute cutaneous lupus erythematosus (SCLE), tongue edema, toxic epidermal necrolysis (TEN), urticaria.
Musculoskeletal and connective tissue disorders: Arthralgia, arthritis, arthropathy, back pain, bone fracture, cramps, fibromyalgia syndrome, fracture of the hip, wrist, or spine, hypertonia, muscle spasms, myalgia, muscular weakness, osteoporosis, polymyalgia rheumatica, rigors.
Renal and urinary disorders: Albuminuria, cystitis, dysuria, glycosuria, hematuria, interstitial nephritis, polyuria, proteinuria, renal failure, urinary frequency, urinary tract infection.
Reproductive system and breast disorders: Dysmenorrhea, genital moniliasis, gynecomastia, impotence, menstrual disorder, vaginitis.
General disorders and administration site conditions: Asthenia, fatigue, fever, flu-like disorder, hernia, increased sweating, malaise, pain.
Investigations: Increased alkaline phosphatase, increased serum gastrin, increased serum glutamic oxaloacetic transaminase, increased serum glutamic pyruvic transaminase, weight gain/loss.
Injury, poisoning and procedural complications: Postoperative pain.