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Pharmacotherapeutic group: Neuroleptics (antipsychotics). ATC code: N05AF01.
Pharmacology: Pharmacodynamics: Flupentixol is a non-sedating antipsychotic drug of the thioxanthene group. Its primary pharmacological action is dopamine blockade. Flupentixol has a high affinity for D1 and D2 receptors. Flupentixol Injection contains the decanoic ester of flupentixol in thin vegetable oil.
Pharmacokinetics: After intramuscular injection, the ester is slowly released from the oil depot and is rapidly hydrolysed to release flupentixol. Flupentixol is widely distributed in the body and extensively metabolized in the liver. Peak circulating levels occur around 7 days after administration.
