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Folic acid should never be given alone or in conjunction with inadequate amounts of vitamin B12 for the treatment of pernicious anemia, undiagnosed megaloblastic anemia or other vitamin B12 deficiency states. Folic acid may produce hematopoietic response in patients with megaloblastic anemia due to vitamin B12 deficiency without preventing aggravation of neurological symptoms, which may lead to subacute combined degeneration of the spinal cord. This product should never be used to treat anemia without a full investigation of the cause.
Administering folic acid to patients with folate dependent tumors should be done with caution.
