Adult Monotherapy for non-small cell lung cancer 1,000 mg/m² given in IV infusion, repeated once wkly for 3 wk, followed by a 1-wk rest period.
Combination w/ cisplatin 3-wk cycle: 1,250 mg/m² given by 30 min IV infusion on days 1 & 8, followed by 1-wk rest period. 4-wk cycle: 1,000 mg/m² given by 30 min IV infusion on days 1, 8 & 15, followed by 1-wk rest period.
Pancreatic adenocarcinoma 1,000 mg/m² given by 30 min IV infusion, repeated once wkly for 7 wk, followed by a wk rest. Subsequent cycles should consist of inj once wkly for 3 consecutive wk out of every 4 wk.
Bladder cancer at the invasive stage in combination w/ cisplatin 1,000 mg/m² given by 30 min IV infusion on days 1, 8 & 15, followed by 1-wk rest period for a 28-day cycle. Cisplatin is given at a recommended dose of 70 mg/m² on day 2.
Breast cancer in combination w/ paclitaxel Paclitaxel 175 mg/m² administered on day 1 over approx 3 hr as IV infusion, followed by gemcitabine 1,250 mg/m² as a 30-min IV infusion on days 1 & 8 of each 21-day cycle.
Ovarian cancer in combination w/ carboplatin 1,000 mg/m² administered on days 1 & 8 of each 21-day cycle as a 30-min IV infusion. After gemcitabine, carboplatin should be given on day 1 to attain a target AUC of 4 mg/mL/min.
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