IM/IV Adult w/ normal renal function 3 mg/kg daily in equally divided doses at 8 hr intervals. Life-threatening infections Up to 5 mg/kg daily in 3-4 equally divided doses, then reduced to 3 mg/kg daily as soon as clinically indicated. Childn 6-7.5 mg/kg daily in equally divided doses at 8 hr intervals; premature or full term neonate >1 wk 2.5 mg/kg every 12 hr.
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