Gesitram Special Precautions

Patients should be cautioned against driving vehicles or operating complicated machinery. Serious and sometimes fatal reactions have occurred when opioids and MAO inhibitors are used concomitantly.
Tramadol should be used with caution in patients with reduced respiratory reverse, elevated intracranial pressure, history of seizures, and history of hypersensitivity to opioids, myasthenia gravis and renal and hepatic dysfunction.
Though there have been no reports of dependence caused by tramadol, this cannot be ruled out. The duration of treatment should be carefully assessed and tramadol should not be continued beyond its usefulness. Intravenous administration should be slow.
Tramadol is usually well tolerated. There have not been reports of dependence even after long term therapy.
Use in Pregnancy & Lactation: It is not clear whether tramadol crosses the placenta or is excreted into the breast milk. This drug should be used during pregnancy and in nursing mothers only if it is considered necessary.