Initial therapy: 1-2 mg once daily. Patient sensitive to hypoglycemics 1 mg once daily & titrated carefully. Max starting dose: >2 mg. Maintenance: 1-4 mg once daily. Max: 8 mg once daily. Upon reaching 2 mg, dose is increased in not more than 2-mg increments at 1-2 wk intervals based on patient's blood glucose response. Monitor HbA1c levels every 3-6 mth. Getryl-metformin combination therapy Adjust the dose of each drug. Getryl-insulin combination therapy Initially, Getryl 8 mg once daily. Start w/ low-dose insulin & do upward adjustments wkly as guided by frequent measurements of fasting blood glucose.
Monitor fasting blood glucose & HbA1c periodically to determine doses given to patient. Hypoglycemia & loss of control of blood glucose. Pregnancy & lactation. Childn.
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