Activated charcoal may be administered in case of overdosage. Hypotension may respond to placing the patient in supine position with the feet raised and the administration of plasma expanders. If hypotension is not corrected, calcium gluconate or calcium chloride should be given intravenously. If hypotension persists, intravenous administration of a sympathomimetic agent such as isoprenaline, dopamine or noradrenaline (norepinephrine) may be given. Dialysis is not useful as amlodipine is highly protein bound.