Uncontrolled hypertension.
Known hypersensitivity to products derived from mammalian cells.
Known hypersensitivity to human albumin.
Known hypersensitivity to any of the excipients of the formulation.
Patients scheduled for major elective surgery, not participating in autologous blood pre-donation program and not having coronary artery disease, peripheral artery disease, carotid arterial disease or stroke, including patients with recent myocardial infarction or stroke.
Surgical patients who for any reason cannot receive adequate antithrombotic prophylaxis.
Patients developing pure red cell aplasia with any erythropoietin.