Sign Out
Chloramphenicol may cause serious and sometimes fatal adverse effects and it should be discontinued immediately on the appearance of toxic symptoms.
A toxic manifestation 'gray syndrome' which is characterized by abdominal hypothermia, progressive pallid cyanosis, irregular respiration and circulatory collapse followed by death has occurred in premature and other newborn infants receiving large doses of chloramphenicol.
Charcoal haemoperfusion was found to be far superior to exchange transfusion in the removal of chloramphenicol from the blood.
