Women w/ non-metastatic disease; osteoporosis &/or history of fractures. Assess postmenopausal status before initiating treatment; bone mineral density prior adjuvant or extended adjuvant treatment. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Renal (CrCl <30 mL/min) & severe hepatic (cirrhosis & Child-Pugh grade C) impairment. May affect ability to drive or operate machinery. Women of childbearing potential, premenopausal women or who recently became postmenopausal.
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