ML-Gacid Dosage/Direction for Use

The capsule must be kept intact and swallowed whole.
Duodenal Ulcer: 20mg once daily for 2 to 4 weeks.
In some duodenal ulcer patients' refractory to other treatment regimens, 40 mg once daily may be effective.
The usual maintenance dose is 10 to 20 mg once daily.
In demonstrated Helicobacter pylori-associated duodenal ulcer, concomitant use of omeprazole and suitable antibiotics may be beneficial.
Gastric Ulcer and Reflux Oesophagitis: A dosage of 20 mg once daily for 4 to 8 weeks is recommended.
In some patients with gastric ulcer or reflux oesophagitis refractory to other treatment regimens, ML-GACID once daily may be effective.
In patients with severe or symptomatic recurrent reflux oesophagitis treatment can be continued with ML-GACID at a dosage of 20 mg once daily.
Zollinger-Ellison Syndrome: An initial dosage of 60 mg once daily is recommended. The dosage should be adjusted to the individual requirements of each patient and treatment continued as long as is clinically required.
More than 90% of patients with severe disease have been maintained on daily doses of 20 mg to 120 mg. If doses required are higher than 80mg daily, it should be divided into twice daily regimens.
Paediatrics: The safety and efficacy of omeprazole in children has not been established.
Elderly: No dose adjustment is required in the elderly.
Impaired Renal Function: No dose adjustment is required in patients with reduced renal function.
Impaired Hepatic Function: Due to an increase in the bioavailability plasma half-life of omeprazole in patients with impaired hepatic function a daily dose of 20 mg is generally adequate.
The long-term safety of omeprazole in patients with renal and hepatic Impairment has not been established