Nocid Dosage/Direction for Use

In the treatment of gastro-oesophageal reflux disease, the usual dose by mouth is 20 to 40 mg once daily for 4 weeks, increased to 8 weeks if necessary; sometimes up to 16 weeks for healing of erosive oesophagitis. For maintenance therapy, treatment can be continued with 20 to 40 mg once daily. Alternatively, for recurring symptoms, an on-demand regimen of 20 mg daily may be given.
The usual dose for the treatment of peptic ulcer disease is 40 mg once daily. Treatment is usually given for 2 to 4 weeks for duodenal ulceration, or for 4 to 8 weeks for benign gastric ulceration.
For the eradication of Helicobacter pylori in peptic ulceration pantoprazole may be combined with two antibacterials in a one-week therapy regimen. Effective regimens include pantoprazole 40 mg twice daily combined with clarithromycin 500 mg twice daily and either amoxicillin 1 g twice daily or metronidazole 400 mg twice daily.
Patients who require prophylaxis for NSAID-associated ulceration may take 20 mg daily.
In the treatment of pathological hypersecretory states such as Zollinger-Ellison syndrome, the initial dose is 80 mg daily, adjusted as required.
Doses of up to 240 mg daily have been used. Daily doses greater than 80 mg should be given in 2 divided doses. Doses of pantoprazole may need to be reduced in patients with hepatic impairment.
Or as prescribed by the physician.