Concomitant administration of Potassium Citrate and a potassium-sparing diuretic (such as triamterene, spironolactone or amlioride) should be avoided, since the simultaneous administration of these agents can produce severe hyperkalemia. Drugs that have slowed gastrointestinal transit time (such as anticholinergics) can be expected to increase the gastrointestinal irritation produced by potassium salts.
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