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Pregnancy: Pregnancy Category X. Triptorelin is contraindicated in women who are or may become pregnant during treatment with this drug. Expected hormonal changes that occur with triptorelin treatment increase the risk of pregnancy loss and fetal harm if the drug is administered to a pregnant woman. The patient should be informed of the potential hazard to the fetus if this drug is used during pregnancy, and the treatment should be discontinued if the patient becomes pregnant while receiving triptorelin.
Lactation: It is not known if triptorelin is distributed in the breast milk. However, since triptorelin slightly decreases prolactin levels, reduced lactation may be observed. Since there are no well-controlled studies on the effect of triptorelin in breastfeeding women and in breastfed infants, and many drugs are excreted in human milk, a decision should be made to either discontinue breastfeeding, or discontinue triptorelin therapy, considering the importance of the drug to the mother.
