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Animal studies have shown no teratogenic effects; however, safe use of Co-Amoxiclav during pregnancy has not been definitely established. Thus, this drug should be used during pregnancy only when the potential benefits justify the possible risks to the fetus. Especially, Co-Amoxiclav should not be administered during first trimester of pregnancy.
During lactation, trace quantities of penicillin can be excreted in breast milk.
