Hypersensitivity reactions including skin rashes, urticaria, eosinophilia, fever, reactions resembling serum sickness & anaphylaxis. Bleeding complications related to hypoprothrombinaemia &/or platelet dysfunction; nephrotoxicity, acute renal tubular necrosis, acute interstitial nephritis; transient increase of liver enzymes; overgrowth of non-susceptible organisms w/ prolonged use.