Hypersensitivity to clomifene citrate or to any ingredient in the product; Pregnancy; Active liver disease or history of liver dysfunction; Hormone-dependent tumors or abnormal uterine bleeding of undetermined origin; Uncontrolled thyroid or adrenal dysfunction; Pituitary or ovarian tumors; Ovarian cysts (other than in association with polycystic ovarian syndrome) and pre-existing endometriosis.