The simultaneous administration of medicaments containing calcium (e.g., acetolyte) may lead to pathological increase of the serum calcium level or intensification.
As the uraemic symptoms improve under Ketoanalogues + Essential amino acids, a possible administration of aluminum hydroxide should be reduced. Pay attention to a reduction of serum phosphate. In order not to interfere with absorption, do not take drugs together with Ketoanalogues + Essential amino acids that form sparingly soluble compounds with calcium (e.g., tetracyclines, quinolones (e.g., ciprofloxacin, norfloxacin), Iron, fluoride, and estramustin-containing drugs). Between the intake of Ketoanalogues + Essential amino acids and drugs from the mentioned categories, a period of at least 2 hours should pass. The susceptibility towards heart/cardio-active glycosides and hence, also the risk of arrhythmia increases with the rise of the blood calcium concentration.