Prevention of nausea & vomiting induced by cytotoxic therapy 5 mg/day on day 1 immediately before cancer chemotherapy as an infusion over 15 min or as slow inj (not <1 min) followed by oral administration on days 2-6.
Patients w/ cardiac rhythm or conduction disturbances. Patients w/ impaired hepatic or renal function, uncontrolled HTN. May affect ability to drive or operate machinery. Pregnancy & lactation. Not recommended in childn.