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SII-ONCO-BCG for intravesical instillation in carcinoma in situ of bladder should not be used in: Impaired immune response irrespective of whether this impairment is congenital or caused by disease, drugs or other therapy.
Positive HIV serology.
Pregnancy and lactation; safety of the mode of therapy in pregnant women, nursing mothers and children has not been evaluated.
Positive tuberculin reaction in conjunction with clinical evidence of existing active tuberculosis.
Urinary tract infections: Treatment should be withheld till urine culture is negative and antibiotic therapy is stopped.
Trauma to urinary bladder.
A patient with fever needs careful evaluation before therapy is instituted.
On going treatment with antitubercular agents.
