Therabloc Adverse Reactions

Cardiovascular System: Potentially serious adverse cardiovascular effects of atenolol include bradycardia, profound hypotension, 2nd- or 3rd-degree atrioventricular (AV) block and precipitation of severe congestive heart failure (CHF).
Central Nervous System: Reversible mental depression progressing to catatonia (an acute reversible syndrome characterized by disorientation of time and place), short-term memory loss, emotional lability with slightly clouded sensorium and decreased performance on neuropsychometrics.
Gastrointestinal: Mesenteric arterial thrombosis and ischemic colitis.
Hematologic: Agranulocytosis.
Allergic: Fever, with aching and sore throat, laryngospasm and respiratory distress.
Others: Wheezing and dyspnea have occurred in patients receiving atenolol and are likely to occur when dosage of the drug exceeds 100 mg daily. Skin rashes and drying of the eyes have also been reported.
The possibility that other adverse effects associated with other β-adrenergic-blocking agents may occur during atenolol therapy should be considered. These include hematologic reactions (ie, agranulocytosis, thrombocytopenic purpura); elevation of cholesterol, plasma total triglycerides and decrease in high-density cholesterol; reversible alopecia; Peyronie's disease; Raynaud's phenomenon; erythematous rash; and impotence.