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Pregnancy: Pregnancy Category C.
In a rat developmental toxicity study, oral administration of 1000 mg Cilostazol/kg/day was associated with decreased fetal weights and increased incidences of cardiovascular, renal, and skeletal anomalies (ventricular septal, aortic arch, and subclavian artery abnormalities; renal pelvic dilation; 14th rib; and retarded ossification).
Lactation: Transfer of Cilostazol into milk has been reported in experimental animals (rats). Because of the potential risk to nursing infants, a decision should be made to discontinue breastfeeding or to discontinue Cilostazol.
