Rosuvastatin is given in an initial dose of 5 to 10 mg once daily, at night, depending on plasma-cholesterol concentrations, cardiovascular risk factors, and risk factor for adverse effects, or as prescribed by the physician. The maintenance dose ranges from 5 to 40 mg once daily, although the 40-mg dose is reserved for patients with high cardiovascular risk who do not achieve their target cholesterol concentration at lower doses and who do not have risk factors for adverse effects.
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