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Trucox

Trucox

celecoxib

Manufacturer:

Flamingo

Distributor:

Trumed

Marketer:

Hexagon Pharma
Concise Prescribing Info
Contents
Celecoxib
Indications/Uses
RA & OA. Adjunct in the treatment of familial adenomatous polyposis (FAP).
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Dosage/Direction for Use
OA 200 mg daily as single or in 2 divided doses. RA 100-200 mg bid. Pain & dysmenorrhea Initially 400 mg followed by an additional 200 mg on the 1st day, then 200 mg bid thereafter. FAP 40 mg bid.
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Administration
May be taken with or without food: Dose for OA/RA may be given w/ or w/o meals, but doses for FAP must be given w/ meals.
Contraindications
History of stroke (CVA), heart attack (MI), CABG, uncontrolled HTN, CHF (NYHA II-V). Severe heart failure, inflammatory bowel disease & renal impairment (CrCl <30 mL/min); asthma & urticaria; previous or active ulceration.
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Special Precautions
Hypersensitivity. Severe hepatic impairment; liver dysfunction, dehydration, anemia, preexisting asthma. Pregnancy.
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Adverse Reactions
Constipation, diverticulitis, dysphagia, eructation, esophagitis, gastritis, GERD, hemorrhoids, hiatal hernia, melena, dry mouth, stomatitis, tenesmus, tooth disorder, vomiting; aggravated HTN, angina pectoris, CAD, MI; abnormal hepatic function, increased SGOT & SGPT; anorexia, anxiety, increased appetite, depression, nervousness, somnolence; albuminuria, cystitis, dysuria, hematuria, micturition frequency, renal calculus, urinary incontinence & UTI.
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Drug Interactions
Changes in plasma conc w/ CYP2C9. Increased plasma conc w/ fluconazole.
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Storage
View Trucox storage conditions for details to ensure optimal shelf-life.
Description
View Trucox description for details of the chemical structure and excipients (inactive components).
Action
View Trucox mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Presentation/Packing
Form
Trucox cap 200 mg
Packing/Price
30's
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