HTN 80 mg once daily, may increase to 160-320 mg (max) if BP is not adequately controlled. Heart failure 40 mg bid, titrate to 80 mg & 160 mg bid of at least 2 wk intervals & as tolerated by patient. MI Initially 20 mg bid, titrated to 40, 80 & 160 mg bid.
Concomitant use w/ an ACE inhibitor & β-blocker is not recommended in patients w/ heart failure. Renal & hepatic insufficiency. Should not be used during pregnancy. Not recommended during lactation.
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