Non-steroidal anti-inflammatory drugs (NSAIDs) may antagonise the antihypertensive effect concurrent use with sympathomimetics may reduce the antihypertensive effects.
Potassium-sparing diuretic: may lead to elevation of serum potassium.
Concurrent administration of sublingual nitroglycerin, long-acting nitrates, beta-blockers or other antianginal agents with Amlodipine may produce additive antihypertensive and antianginal effects.