Varilrix is contraindicated in individuals with severe humoral or cellular immunodeficiency such as: patients with primary or acquired immunodeficiency states with a total lymphocyte count less than 1,200 per mm3;
Patients presenting other evidence of lack of cellular immune competence (e.g. patients with leukaemias, lymphomas, blood dyscrasias, clinically manifest HIV infection);
Patients receiving immunosuppressive therapy including high dose of corticosteroids. See also Precautions.
Varilrix is contraindicated in individuals with known hypersensitivity to neomycin or to any other component of the vaccine (see Description). A history of contact dermatitis to neomycin is not a contraindication.
Varilrix is contraindicated in individuals having shown signs of hypersensitivity after previous administration of varicella vaccine.
Varilrix is contraindicated in pregnant women. Pregnancy should be avoided for one month after vaccination (see Use in Pregnancy & Lactation).