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Dyspepsia: Usual dose: 20 mg daily for 2-4 weeks.
Gastro-esophageal reflux disease: Usual dose: 20 mg once daily for 4 weeks followed by a further 4 to 8 weeks if not fully healed.
Refractory esophagitis: 40 mg daily. Maintenance therapy after healing of esophagitis is 20 mg once daily. In children, doses in the range 0.7 to 1.4 mg per kg bodyweight daily, up to a maximum dose of 40 mg, have been given for 4 to 12 weeks.
Peptic ulcer disease: A single dose of 20 mg by mouth, or 40 mg in severe cases, is given. Treatment is continued for 4 weeks for duodenal ulcer and 8 weeks for gastric ulcer. Where appropriate, a dose of 20 mg once daily may be given for maintenance.
NSAID-associated ulceration: A dose of 20 mg daily.
Zollinger-Ellison syndrome: Initial recommended dosage is 60 mg once daily.
Or as prescribed by a physician.
Prophylaxis of acid aspiration during general anesthesia: 40 mg the evening before the surgery and a further 40 mg two to six hours before the procedure. Or as prescribed by a physician.
