Zithrocin Adverse Reactions

Most frequent adverse effects are gastrointestinal in origin with anorexia, nausea, abdominal discomfort, cramps, flatulence, vomiting and diarrhea. Adverse effects also include pruritus, urticaria, skin rashes as well as occasional cases of anaphylaxis. Stevens-Johnson syndrome and toxic epidermal necrosis have also been reported very rarely. Thrombocytopenia and mild transient neutropenia have been rarely reported in patients taking azithromycin. Azithromycin may aggravate muscle weakness in patients with myasthenia gravis. Other side effects reported include chest pain, melena, vaginitis, headache, taste disturbances, vertigo, dizziness, convulsions, somnolence, tinnitus and fatigue.
Azithromycin may cause reversible sensorineural hearing loss, eosinophilia, acute interstitial nephritis. Effects on fluid and electrolyte homeostasis have also been reported.
Azithromycin like other macrolides, may cause irregular heart beat. Patients at particular risk are those with history of existing QT interval prolongation, low blood levels of potassium or magnesium, and those taking certain drugs used to treat arrythmias.