There was also a tendency to modest weight gain. Some people may also experience anemia and fluid retention. These side effects do not happen in all people.
There was an increase in occurrence of edema in the patients treated with pioglitazone and insulin compared to insulin alone.
Pioglitazone plus insulin developed dyspnea at some point during therapy.
ZolidPlus: In general treatment with ZolidPlus was well tolerated. The possible side effects include: Combination Therapy: Common: Anemia, visual disturbance, increased weight, arthralgia, headache, hematuria, erectile dysfunction. Uncommon: Flatulence.
Individual Active Substances of the Fixed-Dose Combination: Pioglitazone: Common: Upper respiratory tract infection and hypoesthesia. Uncommon: Sinusitis and insomnia.
Metformin HCl: Most Common: Taste disturbance, nausea, vomiting, diarrhea, abdominal pain, loss of appetite. Uncommon: Decrease in vitamin B12 absorption and serum levels, lactic acidosis.
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