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Hypersensitivity to pioglitazone HCl, glimepiride or any of component of Zoliget.
Patients with diabetic ketoacidosis, with or without coma. This condition should be treated with insulin. Those with antihypertensive effect in the presence of insulin; therefore, Zoliget should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
Patients with moderate to severe heart failure or liver problems.
Use in pregnancy & lactation. Children.
Zoliget is not recommended in patients with symptomatic heart failure.
Initiation of Zoliget in patients with established NYHA Class III or IV heart failure is contraindicated.
