Zyriz

Zyriz

cetirizine

Manufacturer:

Interphil

Distributor:

Cathay YSS
Concise Prescribing Info
Contents
Cetirizine HCl
Indications/Uses
Symptomatic relief of allergic conditions including rhinitis & chronic urticaria.
Dosage/Direction for Use
Adult & childn ≥6 yr 10 mg once daily or 5 mg bid. Hepatic & renal impairment Reduce to ½ the usual daily dose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to cetirizine, hydroxyzine, or piperazine derivatives. Hypokalemic patients w/ chronic renal failure undergoing hemodialysis. Childn <6 yr w/ hepatic & renal impairment.
Special Precautions
Discontinue treatment if signs & symptoms of small pustules occur w/ or w/o pyrexia or erythema. Concomitant use w/ alcohol. Patients requiring mental alertness or physical coordination eg, drivers or machine operators. Pregnancy. Not recommended during lactation. Infants & childn (increased risk of antimuscarinic effects). Elderly.
Adverse Reactions
Drowsiness; irritability, insomnia, somnolence, fatigue, dry mouth, pharyngitis, dizziness, headache, abdominal pain, cough, diarrhea, epistaxis, bronchospasm, nausea & vomiting, hypersensitivity manifested by urticarial & fixed drug eruptions, nervousness, rashes, anaphylactic shock, aggression, hallucination, dysgeusia, dyskinesia, dystonia, memory impairment, syncope, tremor, eye pain/swelling, blurred vision, abnormal hepatic function, pruritus, urticaria, acute generalized exanthematous pustulosis, arthralgia, enuresis, urinary retention, erectile dysfunction, malaise, abnormal feeling, pruritus upon w/drawal, increased wt. Autoimmune-mediated hepatotoxicity (possible to develop). Life-threatening hepatitis w/ long-term treatment.
Drug Interactions
Enhanced sedation w/ CNS depressants eg, barbiturates, alcohol, hypnotics, opioid analgesics, anxiolytics sedatives & neuroleptics. Enhanced effects of alcohol & other CNS depressants.
MIMS Class
Antihistamines & Antiallergics
ATC Classification
R06AE07 - cetirizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.
Presentation/Packing
Form
Zyriz FC tab 10 mg
Packing/Price
100's
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