Hypersensitivity to the active substance or to any of the excipients listed in Description.
Women who are or may potentially be pregnant (see Use in Pregnancy & Lactation).
Severe hepatic impairment [Child-Pugh Class C (see Dosage & Administration, Precautions, and Pharmacology: Pharmacokinetics under Actions)].
Abiraterone acetate (Zytiga) with prednisone or prednisolone is contraindicated in combination with Ra-223.