As an adjunct to diet for the reduction of elevated total & LDL-cholesterol levels in patients w/ primary hypercholesterolemia (types IIa & IIb). Primary prevention of coronary events & secondary prevention of CV events.
Liver function tests should be performed at baseline & at 12 wk following initiation of therapy or the elevation of dose. History of liver disease or heavy alcohol ingestion. Marked elevation of CPK levels or diagnosed or suspected myopathy (discontinue drug). Renal impairment, elderly.