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Concurrent use of Clarithromycin with theophylline may be associated with an increase of serum theophylline concentrations.
Single-dose administration of Clarithromycin resulted in increased concentrations of carbamazepine. Blood level monitoring of carbamazepine should be considered.
The following drug interactions have been observed with erythromycin products: Concomitant administration of Clarithromycin and digoxin has been found to result in elevated digoxin levels.
Erythromycin decreases the clearance of triazolam, and thus may increase the pharmacological effect of triazolam.
There have been reports of increased anti-coagulant effects, when erythromycin and oral anticoa-gulant were used concomitantly.
