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Duration of Treatment: Unless specifically prescribed by doctor, Iliadin 0.05%, 0.025% and 0.01% should only be used for short periods of time (5-7 days). A treatment-free period of several days should be preceded by repeated use. Permanent use of decongestant rhinological agents may attenuate their effect. The abuse of local rhinological agents may cause mucosal athrophy and reactive hyperaemia with rhinitis medicamentosa. Longer use of oxymetazoline may cause damage to the mucosal epithelium with inhibition of ciliary activity. This may possible result in irreversible damage to the mucosa with rhinitis sicca. Long term use and overdosage must be avoided, especially in children. Dosage higher than recommended may only be used under medical supervision.