Oramorph Dosage/Direction for Use

Posology: The Oramorph dose is adjusted depending on the severity of pain and with regards to the individual sensitivity of the patient.
Under medical control the dose can be increased depending on the severity of pain and depending on the use of analgesics so far.
For oral use.
The solution should be administered with some liquid (water or juice).
The recommended dose depends on the individual pain condition and is for Adults: initial dose usually 10-30 mg morphine sulfate pentahydrate (corresponding to 5-15 ml Oramorph 2 mg/ml - syrup) every 4-6 hours.
Immediately prior to administration the prescribed Oramorph dose is measured with the aid of the provided measuring pipette of 5 ml, graduated with marks on every 0.25 ml.
Elderly patients: In elderly patients or in patients that should not experience sedation the dosage should be reduced. Older patients (usually 75 years and older) and patients with poor overall physical condition may be sensitive to morphine. Therefore, the adjustment of dose has to be done more carefully and/or the dosage intervals have to be extended. As appropriate, lower dosage strengths have to be given instead.
Patients with impaired liver and/or kidney function: In patients with liver and/or kidney dysfunction and if a delayed gastrointestinal passage is suspected Oramorph should be dosed especially carefully.
Discontinuation of therapy: An abstinence syndrome may be precipitated if opioid administration is suddenly discontinued. Therefore the dose should be gradually reduced prior to discontinuation.