Alvolaxus

Alvolaxus

lactulose

Manufacturer:

Alvogen

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Lactulose
Indications/Uses
Prevention & treatment of portal-systemic encephalopathy (PSE) including hepatic pre-coma & coma. Constipation. Restore regular bowel movements in hemorrhoidectomy patients.
Dosage/Direction for Use
Prevention of PSE Adult 20-30 g (30-45 mL) tid-qid. Adjust dose every 1-2 days to produce 2-3 soft stools/day. Childn 26.7-60 g daily (40-90 mL daily) in divided doses. Adjust dose to produce 2-3 stools/day. Infant 1.7-6.7 g daily (2.5-10 mL daily) in divided doses. Adjust dose to produce 2-3 stools/day. Acute PSE Adult 20-30 g (30-45 mL) every 1 hr to induce rapid laxation. Reduce to 20-30 g (30-45 mL) tid-qid after laxation is achieved, titrate to produce 2-3 soft stools/day. Constipation Adult 10-20 g (15-30 mL) daily. May increase to 40 g (60 mL) daily, if necessary.
Administration
May be taken with or without food.
Contraindications
Patients requiring low galactose diet.
Special Precautions
DM. Soln contains galactose & lactose. Possible inadequate response in patients receiving concomitant oral anti-infective agent. Monitor electrolyte imbalance periodically when used >6 mth or in patients predisposed to electrolyte abnormalities (eg, elderly). Measure serum electrolytes (eg, K, Cl, CO2) periodically in geriatric, debilitated patients who receive treatment for >6 mth. Hepatic disease may predispose patients to electrolyte imbalance. May develop hyponatremia & dehydration in infants.
Adverse Reactions
Dehydration, hypernatremia, hypokalemia; abdominal discomfort & distention, belching, cramping, diarrhea (excessive dose), flatulence, nausea, vomiting.
Drug Interactions
Concomitant use w/ additional laxatives, & neomycin or other oral anti-infective agents. May inhibit desired decrease in fecal pH in colon w/ antacids.
MIMS Class
Laxatives, Purgatives
ATC Classification
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Presentation/Packing
Form
Alvolaxus oral soln 10 g/15 mL
Packing/Price
20 × 1's
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