There is no specific antidote for overdose with Pregabalin. If indicated, elimination of unabsorbed drug may be attempted by gastric lavage; observe usual precautions to maintain the airway. General supportive care of the patient is indicated including monitoring of vital signs and observation of the clinical status of the patient. Contact a certified poison control center for up-to-date information on the management of overdose with pregabalin. Although hemodialysis has not been performed in the few known cases of overdose, it may be indicated by the patient's clinical state or in patients with significant renal function impairment. Standard hemodialysis procedures result in significant clearance of pregabalin (approximately 50% in 4 hours).
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