Binozyt Dosage/Direction for Use

Posology: Adults: Oral azithromycin should be administered as a single daily dose.
For the treatment of sexually transmitted diseases caused by Chlamydia trachomatis, Haemophilus ducreyi, or susceptible Neisseria gonorrheae, the dose is 1000 mg as a single oral dose.
For the treatment of adult patients with community acquired pneumonia (CAP) due to the indicated organisms, the recommended dose of intravenous azithromycin is 500 mg as a single daily dose by the IV route for at least two days. Intravenous Therapy should be followed by oral azithromycin at a single daily dose of 500 mg to complete a 7 to 10 day course of therapy. The timing of the conversion to oral therapy should be done at the discretion of the physician and in accordance with clinical response.
For the treatment of DMAC infections should take 600 mg once daily. Azithromycin should be administered in combination with other antimycobacterial agents that have shown in vitro activity against MAC, including ethambutol at the approved dose.
For prophylaxis against MAC infections should take 1,200 mg as a single dose once a week.
For all other indications the dose is 1,500 mg, to be administered as 500 mg [2 capsules of Binozyt 250 mg] per day for three consecutive days.
In patients with renal impairment: No dose adjustment is necessary in patients with mild to moderate renal impairment (GFR 10-80 ml/min) (see Precautions).
In patients with hepatic impairment: A dose adjustment is not necessary for patients with mild to moderately impaired liver function (see Precautions).
Older people: The same dose as in adult patients is used in older people. Since older patients can be patients with ongoing proarrhythmic conditions a particular caution is recommended due to the risk of developing cardiac arrhythmia and torsades de pointes (see Precautions).
Method of administration: The capsule should be taken at least one hour before meals or no earlier than 2 hours after meals. The capsules must be swallowed whole with sufficient fluid and not chewed.
Please take the dose prescribed by the doctor on 3 successive days, if possible at the same time of day. The duration of use will depend exclusively on the doctor's instructions. Do not stop taking Binozyt treatment without consulting the doctor. If the patient does, the condition could be made worse.
If the patient forgets to take Binozyt, take the intended dose as soon as the patient remembers. Then continue the treatment as normal.