Use in Pregnancy: NSAIDs should be avoided during pregnancy or avoid them unless the potential benefit outweighs the risk. NSAIDs should be avoided during the third trimester because use is associated with a risk of closure of fetal ductus arteriosus in utero and possibly persistent pulmonary hypertension of the newborn. In addition, the onset of labour may be delayed and its duration may be increased.
Use in Lactation: NSAIDs should be used with caution during breast-feeding.