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Hypersensitivity to nebivolol or any ingredient in the formulation.
Liver insufficiency or liver function impairment.
Acute heart failure, cardiogenic shock or episodes of heart failure decompensation requiring i.v. inotropic therapy.
In addition, as with other beta-blocking agents, Nebivolol is contra-indicated in: Sick sinus syndrome, including sino-atrial block; Second and third degree heart block (without a pacemaker); History of bronchospasm and bronchial asthma; Untreated pheochromocytoma; Metabolic acidosis; Bradycardia (heart rate < 60 bpm prior to start therapy); Hypotension (systolic blood pressure < 90 mmHg); Severe peripheral circulatory disturbances.
