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Risk of GI Ulceration, Bleeding and Perforation with Non-steroidal Anti-inflammatory Therapy: Serious gastrointestinal toxicity such as bleeding, ulceration, and perforation, can occur at any time, with or without warning symptoms, in patients treated chronically with non-steroidal anti-inflammatory drugs. Although minor upper gastrointestinal problems, such as dyspepsia, are common, usually developing early in therapy, physicians should remain alert for ulceration and bleeding in patients treated chronically with non-steroidal anti-inflammatory drugs even in the absence of previous GI tract symptoms. In patients observed in clinical trials of several months to two years duration, symptomatic upper GI ulcers, gross bleeding or perforation appear to occur in approximately 1% of patients treated for 3-6 months, and in about 2-4% of patients treated for one year. Physicians should inform patients about the signs and/or symptoms of serious GI toxicity and what steps to take if they occur.
Dosage in excess of those recommended may cause severe liver function damage. Patients suffering from liver or kidney disease should take Paracetamol under medical supervision.
Consult a doctor if no relief is obtained from the recommended dosage.
Do not use continuously for more than 10 days without consulting a doctor.
Do not take with any other paracetamol-containing products.
